Unraveling epigenetics influence on memory formation in mouse brain
© 2024 EPFL
The Bioinformatics Competence Center (BICC) contributed to an exciting study that provided new insights into the role played by epigenetics in memory formation.
Through a successful collaboration with Giulia Santoni (Johannes Gräff's lab), and an in-depth analysis of single-cell multi-omics datasets, the BICC contributed to shedding light on the specific transcriptomics and epigenetics profiles of neurons recruited into the “memory trace”.
For more information please see this news release.
References
Giulia Santoni, Simone Astori, Marion Leleu, Liliane Glauser, Simon A. Zamora, Myriam Schioppa, Isabella Tarulli, Carmen Sandi, Johannes Gräff. Chromatin plasticity predetermines neuronal eligibility for memory trace formation. Science 26 July 2024. DOI: 10.1126/science.adg9982