Opening of a new organoid and stem cell culture laboratory

Organoids are lab-grown, 3D cell structures that mimic some features of real organs. They originate from stem or progenitor cells, which can differentiate into various cell types and organize themselves into functional mini organs. Because of their complexity and their ability to replicate organ-like functions on a small scale, organoids provide a more realistic model for studying biological processes compared to traditional 2D cell cultures.

As a result, organoids play an increasingly important role in biomedical research and represent a promising breakthrough, particularly in the fields developmental biology and personalized medicine, while reducing the need for animal experimentation. Eager to contribute to this technology, the Center of PhenoGenomics and the School of Life Sciences at EPFL are excited to announce the opening of the SCOL (Stem Cell and Organoid Laboratory) in September. This shared space is accessible to all research groups at EPFL and enables the culture of organoids and induced pluripotent stem cells (iPSCs).

SCOL offers access to both P1 and P2 biosafety level laboratories, where scientists can conduct their research in a controlled environment. The labs are equipped with cell culture hoods, incubators, microscopes, cell counters, centrifuges, electroporators and a machine for freezing cells, all available to researchers. The facility is designed to adapt to evolving needs and demands. Additionally, a biobank of mouse organoids, derived from various genetic backgrounds and different organs, is also available.

Members of the community wishing to take advantage of this facility or discover the organoid technology are welcome to contact Dr Andrea Krapp, head of the laboratory, who developed her expertise in this field with Professor Wouter Karthaus.