Metabolism of the hypothalamus.

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© Tous droits réservés par Pink Pfeffernüsse

Effect of manganese chloride on the neurochemical profile of the rat hypothalamus.

The group of Prof. Rolf Gruetter (LIFMET - Laboratory of functional and metabolic imaging) characterized the metabolism of the hypothalamus in rats both under normal conditions and following changes in brain energy homeostasis using a model of DIA (dehydration-induced anorexia) and overnight fasting in rats. The data presented in this study show that it is necessary to perform region-specific 1H-MRS for an accurate characterization of the neurochemical profile of the hypothalamus.

Nathalie Just et al., Journal of Cerebral Blood Flow & Metabolism, doi: 10.1038/jcbfm.2011.92 (2011)